Alok Kumar presenting "Regeneration of liver by Platycladus orientalis extract" at London, UK

2^ns World Congress on Stem Cells and Regenerative Medicine

Date: March 14-15, 2019

Place: London, UK

Link: http://stemcells.alliedacademies.com/europe

Regeneration of liver by Platycladus orientalis extract

Liver is a vital organ of our body performing wide range of functions. Regeneration of liver by through plant extract is safe and having better patient compliance. Present study was aimed at evaluating protective ability of Platycladus orientalis Linn against paracetamol induced hepatotoxicity in rats. When these extracts screened for hepatoprotective activity, the results obtained from paracetamol induced hepatotoxic model in the healthy male Wister rats indicates that, after the treatment with paracetamol there was significant rise in SGOT, SGPT, ALP and total bilirubin levels which were lowered by petroleum ether extract of Platycladus orientalis leaf, sylimarin 25 mg/kg was taken as the standard drug. In the whole process of hepatotoxicity thioacetamide was used for toxified the liver and it showed same result as like paracetamol in toxification.

 

In order to detect the oxidative stress in lipid peroxidation in liver checked it’s in-vivo antioxidant parameter like reduced glutathione (GSH), thiobarbituric acid reactive substances (TBARS), catalase (CAT) and superoxide dismutase (SOD) which justify the antioxidant property of both the plant. Which also justify the hepatoprotective and antioxidant effect of the plant. The biochemical observations were supplemented by histopathological examination of pancreas and liver section. In histopathological observation, it was showed that the petroleum ether extract of Platycladus orientalis possess effectively hepatoprotective property

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